Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
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article | 2024 | Modulation of Alzheimer's disease brain pathology in mice by gut bacterial depletion: the role of IL-17a | Hao, Wenlin; Luo, Qinghua; Tomic, Inge; Quan, Wenqiang; Hartmann, Tobias; Menger, Michael D.; Fassbender, Klaus; Liu, Yang | |
article | 2023 | Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells | Bachmann, Cornel Manuel; Janitschke, Daniel; Lauer, Anna Andrea; Erhardt, Tobias; Hartmann, Tobias; Grimm, Marcus Otto Walter; Grimm, Heike Sabine | |
article | 2023 | Aspartame and Its Metabolites Cause Oxidative Stress and Mitochondrial and Lipid Alterations in SH-SY5Y Cells | Griebsch, Lea Victoria; Theiss, Elena Leoni; Janitschke, Daniel; Erhardt, Vincent Konrad Johannes; Erhardt, Tobias; Haas, Elodie Christiane; Kuppler, Konstantin Nicolas; Radermacher, Juliane; Walzer, Oliver; Lauer, Anna Andrea; Matschke, Veronika; Hartmann, Tobias; Grimm, Marcus Otto Walter; Grimm, Heike Sabine | |
article | 2023 | Vitamin D and Its Analogues: From Differences in Molecular Mechanisms to Potential Benefits of Adapted Use in the Treatment of Alzheimer’s Disease | Thiel, Andrea; Hermanns, Carina; Lauer, Anna Andrea; Reichrath, Jörg; Erhardt, Tobias; Hartmann, Tobias; Grimm, Marcus Otto Walter; Grimm, Heike Sabine | |
article | 2023 | Interprofessional education: a necessity in Alzheimer’s dementia care—a pilot study | Dressel, Katharina; Ablinger, Irene; Lauer, Anna Andrea; Grimm, Heike Sabine; Hartmann, Tobias; Hermanns, Carina; Schwarz, Marcus; Taddey, Tim; Grimm, Marcus Otto Walter | |
article | 2023 | A bidirectional link between sulfatide and Alzheimer's disease | Zimmer, Valerie Christin; Lauer, Anna Andrea; Haupenthal, Viola; Stahlmann, Christoph Peter; Mett, Janine; Grösgen, Sven; Hundsdörfer, Benjamin; Rothhaar, Tatjana; Endres, Kristina; Eckhardt, Matthias; Hartmann, Tobias; Grimm, Heike Sabine; Grimm, Marcus Otto Walter | |
article | 2022 | Methylxanthines Induce a Change in the AD/Neurodegeneration-Linked Lipid Profile in Neuroblastoma Cells | Janitschke, Daniel; Lauer, Anna Andrea; Bachmann, Cornel Manuel; Winkler, Jakob; Griebsch, Lea Victoria; Pilz, Sabrina Melanie; Theiss, Elena Leoni; Grimm, Heike Sabine; Hartmann, Tobias; Grimm, Marcus Otto Walter | |
article | 2022 | Modeling the underlying biological processes in Alzheimer's disease using a multivariate competing risk joint model | van Oudenhoven, Floor M.; Swinkels, Sophie H. N.; Hartmann, Tobias; Rizopoulos, Dimitris | |
article | 2022 | PEX19 Coordinates Neutral Lipid Storage in Cells in a Peroxisome-Independent Fashion | Lyschik, Sven; Lauer, Anna A.; Roth, Tanja; Janitschke, Daniel; Hollander, Markus; Will, Thorsten; Hartmann, Tobias; Kopito, Ron R.; Helms, Volkhard; Grimm, Marcus O. W.; Schrul, Bianca | |
article | 2022 | Vitamin B12 Attenuates Changes in Phospholipid Levels Related to Oxidative Stress in SH-SY5Y Cells | Theiss, Elena Leoni; Griebsch, Lea Victoria; Lauer, Anna Andrea; Janitschke, Daniel; Erhardt, Vincent Konrad Johannes; Haas, Elodie Christiane; Kuppler, Konstantin Nicolas; Radermacher, Juliane; Walzer, Oliver; Portius, Dorothea; Grimm, Heike Sabine; Hartmann, Tobias; Grimm, Marcus Otto Walter | |
article | 2022 | The Influence of Acitretin on Brain Lipidomics in Adolescent Mice : Implications for Pediatric and Adolescent Dermatological Therapy | Lauer, Anna A.; Nguyen, Vu Thu Thuy; Janitschke, Daniel; dos Santos Guilherme, Malena; Bachmann, Cornel M.; Grimm, Heike S.; Hartmann, Tobias; Endres, Kristina; Grimm, Marcus O. W. | |
article | 2022 | Towards new nutritional policies for brain health: A research perspective on future actions | Adan, Roger A. H.; Cirulli, Francesca; Dye, Louise; Higgs, Suzanne; Aarts, Kristien; van der Beek, Eline M.; Buitelaar, Jan K.; Destrebecq, Frédéric; De Witte, Elke; Hartmann, Tobias; Korosi, Aniko; Libuda, Lars; Dickson, Suzanne L. | |
article | 2021 | Shotgun lipidomics of liver and brain tissue of Alzheimer's disease model mice treated with acitretin | Lauer, Anna A.; Janitschke, Daniel; Dos Santos Guilherme, Malena; Nguyen, Vu Thu Thuy; Bachmann, Cornel M.; Qiao, Sen; Schrul, Bianca; Boehm, Ulrich; Grimm, Heike S.; Hartmann, Tobias; Endres, Kristina; Grimm, Marcus O. W. | |
article | 2021 | Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial | Rosenberg, Anna; Solomon, Alina; Soininen, Hilkka; Visser, Pieter Jelle; Blennow, Kaj; Hartmann, Tobias; Kivipelto, Miia | |
article | 2021 | 36-month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's disease | Soininen, Hilkka; Solomon, Alina; Visser, Pieter Jelle; Hendrix, Suzanne B.; Blennow, Kaj; Kivipelto, Miia; Hartmann, Tobias | |
article | 2021 | Methylxanthines and Neurodegenerative Diseases: An Update | Janitschke, Daniel; Lauer, Anna A.; Bachmann, Cornel M.; Grimm, Heike S.; Hartmann, Tobias; Grimm, Marcus O. W. | |
article | 2021 | Targeted Lipidomics of Mitochondria in a Cellular Alzheimer’s Disease Model | Kurokin, Irina; Lauer, Anna Andrea; Janitschke, Daniel; Winkler, Jakob; Theiss, Elena Leoni; Griebsch, Lea Victoria; Pilz, Sabrina Melanie; Matschke, Veronika; van der Laan, Martin; Grimm, Heike Sabine; Hartmann, Tobias; Grimm, Marcus Otto Walter | |
article | 2021 | Impact of Vitamin D3 Deficiency on Phosphatidylcholine-/Ethanolamine, Plasmalogen-, Lyso-Phosphatidylcholine-/Ethanolamine, Carnitine- and Triacyl Glyceride-Homeostasis in Neuroblastoma Cells and Murine Brain | Lauer, Anna Andrea; Griebsch, Lea Victoria; Pilz, Sabrina Melanie; Janitschke, Daniel; Theiss, Elena Leoni; Reichrath, Jörg; Herr, Christian; Beisswenger, Christoph; Bals, Robert; Valencak, Teresa Giovanna; Portius, Dorothea; Grimm, Heike Sabine; Hartmann, Tobias; Grimm, Marcus Otto Walter | |
article | 2021 | Medium-Chain Length Fatty Acids Enhance Aβ Degradation by Affecting Insulin-Degrading Enzyme | Mett, Janine; Lauer, Anna A.; Janitschke, Daniel; Griebsch, Lea V.; Theiss, Elena L.; Grimm, Heike S.; Koivisto, Hennariikka; Tanila, Heikki; Hartmann, Tobias; Grimm, Marcus O. W. | |
article | 2021 | LipiDiDiet: Multinutrient im frühen Alzheimer Stadium | Hartmann, Tobias | |
article | 2021 | A competing risk joint model for dealing with different types of missing data in an intervention trial in prodromal Alzheimer's disease | van Oudenhoven, Floor M.; Swinkels, Sophie H. N.; Soininen, Hilkka; Kivipelto, Miia; Hartmann, Tobias; Rizopoulos, Dimitris | |
article | 2020 | World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia | Kivipelto, Miia; Mangialasche, Francesca; Snyder, Heather M.; Allegri, Ricardo; Andrieu, Sandrine; Arai, Hidenori; Baker, Laura; Belleville, Sylvie; Brodaty, Henry; Brucki, Sonia M.; Calandri, Ismael; Caramelli, Paulo; Chen, Christopher; Chertkow, Howard; Chew, Effie; Choi, Seong H.; Chowdhary, Neerja; Crivelli, Lucía; Torre, Rafael De La; Du, Yifeng; Dua, Tarun; Espeland, Mark; Feldman, Howard H.; Hartmanis, Maris; Hartmann, Tobias; Heffernan, Megan; Henry, Christiani J.; Hong, Chang H.; Håkansson, Krister; Iwatsubo, Takeshi; Jeong, Jee H.; Jimenez-Maggiora, Gustavo; Koo, Edward H.; Launer, Lenore J.; Lehtisalo, Jenni; Lopera, Francisco; Martínez-Lage, Pablo; Martins, Ralph; Middleton, Lefkos; Molinuevo, José L.; Montero-Odasso, Manuel; Moon, So Y.; Morales-Pérez, Kristal; Nitrini, Ricardo; Nygaard, Haakon B.; Park, Yoo K; Peltonen, Markku; Qiu, Chengxuan; Quiroz, Yakeel T.; Raman, Rema; Rao, Naren; Ravindranath, Vijayalakshmi; Rosenberg, Anna; Sakurai, Takashi; Salinas, Rosa M.; Scheltens, Philip; Sevlever, Gustavo; Soininen, Hilkka; Sosa, Ana L.; Suemoto, Claudia K.; Tainta-Cuezva, Mikel; Velilla, Lina; Wang, Yongxiang; Whitmer, Rachel; Xu, Xin; Bain, Lisa J.; Solomon, Alina; Ngandu, Tiia; Carrillo, Maria C. | |
article | 2020 | The impact of capsaicinoids on APP processing in Alzheimer's disease in SH-SY5Y cells | Grimm, Marcus O.W.; Blümel, Tamara; Lauer, Anna A.; Janitschke, Daniel; Stahlmann, Christoph; Mett, Janine; Haupenthal, Viola J.; Miederer, Anna-Maria; Niemeyer, Barbara A.; Grimm, Heike S.; Hartmann, Tobias | |
article | 2020 | Nutrition and the ageing brain: Moving towards clinical applications | Flanagan, Emma; Lamport, Daniel; Brennan, Lorraine; Burnet, Philip; Calabrese, Vittorio; Cunnane, Stephen C.; de Wilde, Martijn C.; Dye, Louise; Farrimond, Jonathan A.; Emerson Lombardo, Nancy; Hartmann, Tobias; Hartung, Thomas; Kalliomäki, Marko; Kuhnle, Gunther G.; La Fata, Giorgio; Sala-Vila, Aleix; Samieri, Cécilia; Smith, A David; Spencer, Jeremy P. E.; Thuret, Sandrine; Tuohy, Kieran; Turroni, Silvia; Vanden Berghe, Wim; Verkuijl, Martin; Verzijden, Karin; Yannakoulia, Mary; Geurts, Lucie; Vauzour, David | |
article | 2020 | Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells | Janitschke, Daniel; Lauer, Anna A.; Bachmann, Cornel M.; Seyfried, Martin; Grimm, Heike S.; Hartmann, Tobias; Grimm, Marcus O. W. | |
article | 2020 | Regulatory feedback cycle of the insulin-degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer's disease | Lauer, Anna A.; Mett, Janine; Janitschke, Daniel; Thiel, Andrea; Stahlmann, Christoph P.; Bachmann, Cornel M.; Ritzmann, Felix; Schrul, Bianca; Müller, Ulrike C.; Stein, Reuven; Riemenschneider, Matthias; Grimm, Heike S.; Hartmann, Tobias; Grimm, Marcus O. W. | |
article | 2020 | Elevated Testosterone Level and Urine Scent Marking in Male 5xFAD Alzheimer Model Mice | Gadomsky, Lisa; Dos Santos Guilherme, Malena; Winkler, Jakob; van der Kooij, Michael A.; Hartmann, Tobias; Grimm, Marcus O. W.; Endres, Kristina | |
article | 2019 | Effect of Caffeine and Other Methylxanthines on Aβ-Homeostasis in SH-SY5Y Cells | Janitschke, Daniel; Nelke, Christopher; Lauer, Anna Andrea; Regner, Liesa; Winkler, Jakob; Thiel, Andrea; Grimm, Heike Sabine; Hartmann, Tobias; Grimm, Marcus Otto Walter | |
article | 2019 | Profiling of Alzheimer's disease related genes in mild to moderate vitamin D hypovitaminosis | Grimm, Marcus O. W.; Lauer, Anna A.; Grösgen, Sven; Thiel, Andrea; Lehmann, Johannes; Winkler, Jakob; Janitschke, Daniel; Herr, Christian; Beisswenger, Christoph; Bals, Robert; Grimm, Heike S.; Hartmann, Tobias | |
article | 2019 | Using joint models to disentangle intervention effect types and baseline confounding: an application within an intervention study in prodromal Alzheimer's disease with Fortasyn Connect | van Oudenhoven, Floor M; Swinkels, Sophie H. N.; Hartmann, Tobias; Soininen, Hilkka; van Hees, Anneke M. J.; Rizopoulos, Dimitris | |
article | 2019 | Transcriptional repression of the ectodomain sheddase ADAM10 by TBX2 and potential implication for Alzheimer's disease | Reinhardt, Sven; Schuck, Florian; Stoye, Nicolai; Hartmann, Tobias; Grimm, Marcus O. W.; Pflugfelder, Gert; Endres, Kristina | |
article | 2019 | Alzheimer's Disease Composite Score: A Post-Hoc Analysis Using Data from the LipiDiDiet Trial in Prodromal Alzheimer's Disease | Hendrix, Suzanne B.; Soininen, Hilkka; van Hees, Anneke M. J.; Ellison, Noel; Visser, Pieter Jelle; Solomon, Alina; Attali, A.; Blennow, Kay; Kivipelto, Miia; Hartmann, Tobias | |
article | 2018 | Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion | Barbero-Camps, Elisabet; Roca-Agujetas, Vicente; Bartolessis, Isabel; de Dios, Cristina; Fernández-Checa, Jose C.; Marí, Montserrat; Morales, Albert; Hartmann, Tobias; Colell, Anna | |
article | 2018 | World Wide Fingers will advance dementia prevention | Kivipelto, Miia; Mangialasche, Francesca; Ngandu, Tiia; Eg, Nuñez Martín, Eg, Jorge José; Kivipelto, Miia; Ngandu, Tiia; Soininen, Hilkka; Tuomilehto, Jaakko; Lindström, Jaana; Solomon, Alina; Mangialasche, Fransesca; Sindi, Shireen; Baker, Laura; Whitmer, Rachel; Espeland, Mark; Du, Yifeng; Wang, Yongxiang; Qiu, Chengxuan; Chen, Christopher; Middleton, Lefkos; Hartmann, Tobias | |
article | 2018 | Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model | Verheijen, Bert M.; Stevens, Jo A. A.; Gentier, Romina J. G.; van 't Hekke, Christian D.; van den Hove, Daniel L. A.; Hermes, Denise J. H. P.; Steinbusch, Harry W. M.; Ruijter, Jan M.; Grimm, Marcus O. W.; Haupenthal, Viola J.; Annaert, Wim; Hartmann, Tobias; van Leeuwen, Fred W. | |
article | 2017 | Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation | Grimm, Marcus O. W.; Thiel, Andrea; Lauer, Anna A.; Winkler, Jakob; Lehmann, Johannes; Regner, Liesa; Nelke, Christopher; Janitschke, Daniel; Benoist, Celine; Streidenberger, Olga; Stötzel, Hannah; Endres, Kristina; Herr, Christian; Beißwenger, Christoph; Grimm, Heike S.; Bals, Robert; Lammert, Frank; Hartmann, Tobias | |
article | 2017 | 24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial | Soininen, Hilkka; Solomon, Alina; Visser, Pieter Jelle; Hendrix, Suzanne B.; Blennow, Kaj; Kivipelto, Miia; Hartmann, Tobias; Hallikainen, Ilona; Hallikainen, Merja; Helisalmi, Seppo; Lappalainen, Tarja; Liu, Yawu; Paajanen, Teemu; Wahlund, Lars-Olof; Freund-Levi, Yvonne; Andreasen, Niels; Hagman, Göran; Lindblom, Stina; Fassbender, Klaus; Riemenschneider, Matthias; Grimm, Marcus O. W.; Klees-Rollmann, Aline; Luley, Maxine; Lyros, Epameinondas; Schomburg, Robert; Kennel, Jennifer; Ramelli, Daniela; Frölich, Lutz; Hausner, Lucrezia; Laske, Christoph; Leyhe, Thomas; Mychajliw, Christian; Koehler, Niklas; Schiekofer, Stephan; Klünemann, Hans; Schröder, Johannes; Lütjohann, Dieter; Scheltens, Philip; van Rossum, Ineke; Scheltens, Nienke; Bertens, Daniela; ten Kate, Mara; Barkhof, Frederik; Henselmans, Johanna M. L.; Roks, Gerwin; van Hees, Anneke M. J.; Ellison, Noel | |
article | 2017 | APP Function and Lipids: A Bidirectional Link | Grimm, Marcus O. W.; Mett, Janine; Grimm, Heike S.; Hartmann, Tobias | |
article | 2017 | Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model | Brandscheid, Carolin; Schuck, Florian; Reinhardt, Sven; Schäfer, Karl-Herbert; Pietrzik, Claus U.; Grimm, Marcus O. W.; Hartmann, Tobias; Schwiertz, Andreas; Endres, Kristina | |
article | 2017 | Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer's disease: a rationale for multi-nutrient dementia prevention | Grimm, Marcus O. W.; Michaelson, Daniel M.; Hartmann, Tobias | |