Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
---|
article | 2024 | SNPs in cytochromes P450 catalyzing cholesterol degradation in brain are associated with Parkinson's disease | Petkova-Kirova, Polina; Kolchina, Anastasia; Baas, Stephan; Wagenpfeil, Gudrun; Unger, Marcus Michael; Schulze-Hentrich, Julia Maria; Bernhardt, Rita | |
article | 2023 | SNPs in cytochrome P450 genes decide on the fate of individuals with genetic predisposition to Parkinson’s disease | Petkova-Kirova, Polina; Baas, Stephan; Wagenpfeil, Gudrun; Hartz, Philip; Unger, Marcus Michael; Bernhardt, Rita | |
article | 2022 | Structural comparison of the cytochrome P450 enzymes CYP106A1 and CYP106A2 provides insight into their differences in steroid conversion | Carius, Yvonne; Hutter, Michael; Kiss, Flora; Bernhardt, Rita; Lancaster, C. Roy D. | |
article | 2021 | Resurrection and characterization of ancestral CYP11A1 enzymes | Hartz, Philip; Strohmaier, Silja J.; El-Gayar, Basma M.; Abdulmughni, Ammar; Hutter, Michael C.; Hannemann, Frank; Gillam, Elizabeth M. J.; Bernhardt, Rita | |
article | 2020 | A Novel Thermostable Cytochrome P450 from Sequence-Based Metagenomics of Binh Chau Hot Spring as a Promising Catalyst for Testosterone Conversion | Nguyen, Kim-Thoa; Nguyen, Ngọc-Lan; Tung, Nguyen Van; Nguyen, Huy Hoang; Milhim, Mohammed; Le, Thi-Thanh-Xuan; Lai, Thi-Hong-Nhung; Phan, Thi-Tuyet-Minh; Bernhardt, Rita | |
article | 2020 | Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols | Lebouvier, Nicolas; Pagniez, Fabrice; Na, Young Min; Shi, Da; Pinson, Patricia; Marchivie, Mathieu; Guillon, Jean; Hakki, Tarek; Bernhardt, Rita; Yee, Sook Wah; Simons, Claire; Lézé, Marie-Pierre; Hartmann, Rolf W.; Mularoni, Angélique; Le Baut, Guillaume; Krimm, Isabelle; Abagyan, Ruben; Le Pape, Patrice; Le Borgne, Marc | |
article | 2020 | Characterization of the Stereoselective P450 Enzyme BotCYP Enables the In Vitro Biosynthesis of the Bottromycin Core Scaffold | Adam, Sebastian; Franz, Laura; Milhim, Mohammed; Bernhardt, Rita; Kalinina, Olga V.; Koehnke, Jesko | |
article | 2019 | Identification and circumvention of bottlenecks in CYP21A2-mediated premedrol production using recombinant Escherichia coli | König, Lisa; Brixius-Anderko, Simone; Milhim, Mohammed; Tavouli-Abbas, Daniela; Hutter, Michael C.; Hannemann, Frank; Bernhardt, Rita | |
article | 2019 | CYP109E1 from Bacillus megaterium Acts as a 24- and 25-Hydroxylase for Cholesterol | Putkaradze, Natalia; Litzenburger, Martin; Hutter, Michael Christopher; Bernhardt, Rita | |
article | 2018 | Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone | Khatri, Yogan; Jóźwik, Ilona K.; Ringle, Michael; Ionescu, Irina Alexandra; Litzenburger, Martin; Hutter, Michael Christopher; Thunnissen, Andy-Mark W. H.; Bernhardt, Rita | |