Please use this identifier to cite or link to this item:
doi:10.22028/D291-44929
Title: | Subthreshold nanosecond laser therapy for chronic central serous chorioretinopathy: A prospective study |
Other Titles: | Thérapie au subthreshold nanolaser pour la choriorétinopathie centrale séreuse chronique : une étude prospective |
Author(s): | Fraenkel, D. Kaymak, H. Hartmann, M. Aljundi, W. Munteanu, C. Seitz, B. Abdin, A. D. |
Language: | English |
Title: | Journal francais d'ophtalmologie |
Volume: | 48 |
Issue: | 3 |
Publisher/Platform: | Elsevier |
Year of Publication: | 2025 |
Free key words: | Central serous chorioretinopathy Pachychoroid Subthreshold nanosecond laser Subretinal fluid Microperimetry Choriorétinopathie centrale séreuse Pachychoroïde Subthreshold nanolaser Liquide sous-rétinien Micropérimetrie |
DDC notations: | 610 Medicine and health |
Publikation type: | Journal Article |
Abstract: | Purpose. — To investigate the morphologic and functional outcomes of nanosecond subthreshold
(ST) laser treatment for patients with chronic central serous chorioretinopathy (CSC).
Methods. — In this prospective study, 44 patients were treated with the ST nanosecond laser
with a follow-up period of 12 months. All target variables were measured at 1, 3, 6 and 12
months after the first laser treatment.
Results. — This study showed a significant improvement in macular sensitivity (MS), a significant
reduction in central macular thickness (CMT) as well as a significant reduction in subretinal
fluid height (SRF) after 3 months of treatment. The subfoveal choroidal thickness (SFCT) was
significantly reduced after 12 months of treatment. However, the best-corrected visual acuity
(BCVA) (logMAR) did not change significantly at any time during the study. A high proportion
of patients (85%) showed complete resolution of SRF after 12 months, indicating a positive
response to treatment in the majority of our patients. Conclusion. — This study showed statistically significant functional improvement in MS as well
as significant anatomical reduction in CMT, SFCT and SRF height in CSC patients treated with
ST nanosecond laser therapy. Patients with higher SRF at baseline required repeated laser
treatments to achieve complete resolution of the SRF. Objectif. — Étudier les resultats ´ morphologiques et fonctionnels du traitement au subthreshold (ST) nanolaser pour les patients atteints de chorioretinopathie ´ centrale sereuse ´ chronique (CCS). Methodes. ´ — Dans cette etude ´ prospective, 44 patients ont et ´ e´ traites´ au ST nanolaser avec une periode ´ de suivi de 12 mois. Toutes les variables ont et ´ e´ mesurees ´ à 1, 3, 6 et 12 mois après le premier traitement au laser. Resultats. ´ — Cette etude ´ a demontr ´ e´ une amelioration ´ significative de la sensibilite´ maculaire (SM) et une reduction ´ significative de l’epaisseur ´ maculaire centrale (EMC), ainsi que de la hauteur du liquide sous-retinien ´ (LSR) après 3 mois de traitement. L’epaisseur ´ choroïdienne sous-foveale ´ (ECSF) n’a et ´ e´ significativement reduite ´ qu’après 12 mois de traitement. Cependant, la meilleure acuite´ visuelle corrigee´ (MAVC) (logMAR) n’a pas change´ de manière significative durant l’etude. ´ La majorite´ des patients (85 %) a montre´ une resolution ´ complète du LSR après 12 mois, ce qui indique une reponse ´ positive au traitement. Conclusion. — Cette etude ´ a demontr ´ e´ une amelioration ´ statistiquement significative de la SM ainsi qu’une reduction ´ significative de l’EMT, de l’ECSF et de la hauteur du LSR chez les patients atteints de CCS traites´ au ST nanolaser. Les patients presentant ´ un LSR plus elev ´ e´ au depart ´ ont dû subir plusieurs traitements pour obtenir une resolution ´ complète du LSR. |
DOI of the first publication: | 10.1016/j.jfo.2024.104372 |
URL of the first publication: | https://doi.org/10.1016/j.jfo.2024.104372 |
Link to this record: | urn:nbn:de:bsz:291--ds-449295 hdl:20.500.11880/39888 http://dx.doi.org/10.22028/D291-44929 |
ISSN: | 0181-5512 |
Date of registration: | 2-Apr-2025 |
Faculty: | M - Medizinische Fakultät |
Department: | M - Augenheilkunde |
Professorship: | M - Prof. Dr. Berthold Seitz |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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